Site-2 proteases (S2P) belong to the M50 family of metalloproteases, which typically perform essential roles by mediating activation of membrane-bound transcription factors through regulated intramembrane proteolysis (RIP).Protease-dependent liberation of dormant transcription factors triggers diverse cellular responses, such as sterol regulation,
Building a neurocognitive profile of suicidal risk in severe mental disorders
Abstract Background Research on the influence of neurocognitive factors on suicide risk, regardless of the diagnosis, is inconsistent.Recently, suicide risk studies propose applying a trans-diagnostic framework in line with the launch of the Research Domain 7NGB Criteria Cognitive Systems model.In the present study, we highlight the extent of cogni
Diversities of Design: Celebrating Plurality in the Anthropocene
Within an Australian context, Enesco the realisation of decarbonised and de-colonial futures requires scrutiny of the socio-political industrial complex upon which the contemporary Australian settler-colonial project was founded.Central to this scrutiny is the need to investigate, contemplate and address a history of systemic racial violence and it
Micropollutant removal capacity and stability of aquaporin incorporated biomimetic thin-film composite membranes
7NGB Aquaporin incorporated nanofiltration membranes have high potential for future applications on separation processes.In this study, performance of biomimetic thin-film composite membranes containing Halomonas elongata and Escherichia coli aquaporins with different affinity tags for the removal of micropollutants was investigated.% rejection of